Crop traits are shaped less by which genes a plant carries than by how, where and when those genes are expressed, in the right tissue, stage and condition. That control sits in regulatory DNA, and it is hard to read from sequence alone. Annogen helps crop developers find and validate the regulatory sequences, variants and gain-of-function edits that unlock new traits, measured directly in your crop, not predicted.

Functionally screen promoters and their variants at an unprecedented scale and sensitivity.

Typical solutions for crop breeders

Non-coding variant screening

We measure which non-coding variants actually shift expression, so you know which to select from an EMS population or introduce by targeted editing to reach your trait.

Genome-wide regulatory element discovery

Annogen uncovers native regulatory elements for precise gene expression.

Lab-in-a-loop training data

Generate bespoke, highly sensitive data sets to train and improve your ML/AI models 

Tailored promoter development

Develop crop-specific promoters around the expression needs of your trait.

Other expression engineering solutions

Generate large-scale plant data to improve regulatory element prediction and design.

What we believe

Depth over shortcuts

We don’t settle for good enough. We explore the full design
space to understand what works best, instead of generating quick designs based on limited available data.

Proof over assumption

Everything we do is grounded in real experimental data. No black boxes, no guesswork. We deliver validated designs rather than predictions to be validated. 

Control as a principle

We believe biological systems can be understood, designed and controlled. That belief drives how we design, test and optimize our gene expression systems. 

Why choose Annogen?

We’re always happy to hear from you. Send us a message and we’ll make sure it reaches the right person.

Design and measurement together

We combine computational design with high-throughput experimental screening to identify what performs, not just what looks promising in a model.

Experience that improves predictability 

With more than a decade of promoter development experience, we can assess feasibility early, guide realistic timelines and tell you when expectations need adjusting.

Datasets built around your biology

When existing data does not cover your expression question, we generate the dataset your therapy needs in the biological system that matters.

Trusted by

Our platform

Platform 1

SuRE™

Identify the regulatory changes worth validating in plants. 

SuRE™ empirically screens promoters, enhancers and their variants at scale in plant-relevant systems, revealing which changes shift expression in the direction your trait requires.

Together, let’s shape what comes next.

Let’s start with your crop.

Tell us the trait, the gene and the change you are chasing, and we will show you how SuRE™ can de-risk regulatory decisions ahead, before they reach a plant.

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