by admin | Oct 1, 2024 | Application notes, SURE Technology
standing the challenge: the right place, the right time The development of cell and gene therapies is a complex and time-consuming process that depends on therapeutic genes being expressed in the right tissues, at the right time and at the right dosage. A key...
by admin | Sep 18, 2024 | Poster, SURE Technology
Download Poster Identify Strong Human Promoters for T-Cell Activation Download the Annogen SuRE™ poster to learn how SuRE™ technology screens millions of gene regulatory elements (GREs) to find the best combinations for T-cell activation. See how this approach...
by admin | Sep 18, 2024 | AIM Technology, Poster
Download Poster Discover Optimal Genomic Sites for Cell Therapy Download the Annogen AIM™ poster to see how AIM™ technology helps identify optimal genomic sites for transgene expression in cell therapies. This method uses integration mapping to find sites with...
by admin | Jul 23, 2024 | Uncategorized
Article – Nature Biotechnology (2016) Genome-wide mapping of autonomous promoter activity in human cells In this landmark paper, Van Arensbergen et al. first present ‘Survey of Regulatory Elements’ (SuRE), a method that exhaustively assays genomic regulatory...
by admin | Apr 1, 2024 | Blog
With more than 5,000 gene therapies in the clinic today [link], decades of promise finally seem to deliver treatments for dozens of rare diseases. Safety and effectiveness are however still major concerns, with short-lived and off-target expression being the main...
